Primary Antibody Matched Pairs
Medchemexpress LLC LOX-1/OLR1 Rat HEK 10ug
The LOX-1/OLR1 protein plays an important role as a receptor that recognizes internalizes and degrades oxidatively modified low-density lipoprotein (oxLDL) a marker of atherosclerosis in vascular endothelial cells OxLDL induces endothelial dysfunction triggering pro-inflammatory responses oxidative conditions and apoptosis LOX-1/OLR1 Protein Rat (HEK293 His) is the recombinant rat-derived LOX-1/OLR1 protein expressed by HEK293 with N-His labeled tag
Biotium NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis)(CPTC-NME2-2), CF568 conjugate, 0.1mg/mL
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have
Biotium MMP3 (Marker of Metastasis and Rheumatoid Arthritis)(rMMP3/1730), CF568 conjugate, 0.1mg/mL
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-3, MMP-10 and MMP-11 (also designated stromelysin-1, 2 and 3, respectively) activate procollagenase. MMP-3 activation of procollagenase can occur via two pathways. Direct activation by MMP-3 is slow and activation by MMP-3 in conjunction with tissue or plasma proteinases is rapid. MMP-10 is expressed in small intestine, and at lower levels in lung and heart. MMP-11 is specifically expressed in stromal cells of breast carcinomas and contributes to epithelial cell malignancies. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer e
Biotium NME2 / nm23-H2 / NDPK-B (Suppressor of Metastasis)(CPTC-NME2-2), CF647 conjugate, 0.1mg/mL
The nm23 gene, a potential suppressor of metastasis, was originally identified by differential hybridization between two murine melanoma sub-lines, one with a high and the second with a low metastatic capacity. Highly metastatic sub-lines exhibit much lower levels of nm23 than less metastatic cells. Based on sequence analysis, nm23 appears highly related to nucleotide diphosphate kinases (NDP). In humans, NDP kinases A and B are identical to two isotypes of human nm23 homologs, namely nm23-H1 and H2, respectively. nm23-H2 is identical in sequence to PuF, a transcription factor that binds to nuclease hypersensitive elements at positions 142 to 115 of the human c-Myc promotor. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have
Biotium CD79b (B-Cell Marker)(rIGB/1842), CF488A conjugate, 0.1mg/mL
CD79 (also designated Ig chains, designated CD79B or B29. The B cell antigen receptor complex (BCR) is formed by the association of CD79 with a membrane immunoglobulin, such as IgM or IgD. The membrane immunoglobulins IgM and IgD achieve surface expression and antigen presentation function in response to CD79 association. The cytoplasmic tails of both CD79A and CD79B contain an ITAM (immuno-receptor tyrosine-based activation) motif, which acts to initiate the BCR signaling reactions by binding to and activating tyrosine kinases. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.
Biotium Perforin-1 (Pore Forming Protein) (Apoptosis Marker)(PRF1/2467), CF405S conjugate, 0.1mg/mL
Perforin is a pore-forming protein that leads to osmotic lysis of the target cells and subsequently enables granzymes to enter the target cells and activate apoptosis. Perforin has structural and functional similarities to complement component 9 (C9). Like C9, this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. It is one of the main cytolytic proteins of cytolytic granules, and is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2), a rare and lethal autosomal recessive disorder of early childhood. The expression of perforin is reportedly upregulated in activated CD8 T-cells, natural killer cells and some CD4 T-cells. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjug
Biotium Thymidylate Synthase (5-FU Resistance Marker)(rTYMS/1884), CF594 conjugate, 0.1mg/mL
Recognizes a protein of 36 kDa, identified as Thymidylate Synthase (TS) (EC 2. 1. 1. 45). It converts deoxyuridine monophosphate (dUMP) to deoxythymidine monophosphate (dTMP), which is essential for DNA biosynthesis. TS is also a critical target for the fluoropyrimidines, an important group of antineoplastic drugs that are widely used in the treatment of solid tumors. Both 5-FU and fluorodeoxyuridine are converted in tumor cells to FdUMP which inactivates TS by formation of a ternary covalent complex in the presence of the folate cofactor 5, 10-methylenetetrahydrofolate. Expression of TS protein has been reported to associate with response to 5-fluorouracil (5-FU) in human colorectal, gastric, head and neck, and breast carcinomas. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommende
Human LTF ELISA Pair Set 5PP (Sino Biological)
Each vial contains 180 ng of recombinant Human Lactotransferrin / LTF. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 5000 pg/mL is recommended.
American Research Products Inc Anti MSLN Mesothelin RG7600
Anti-Human MSLN/Mesothelin (RG7600) Research Grade
Cusabio Technology LLC HUMAN CD86 molecule ELISA KIT
This kit detects CD86 in human serum plasma and tissue homogenates using a quantitative sandwich ELISA methodology Designed for precise measurement it offers a detection range of 0 312 ng/mL to 20 ng/mL with a sensitivity threshold of 0 078 ng/mL ensuring reliable analysis of low-abundance samples The assay requires a sample volume of 50-100 L and involves an incubation period of 1-5 hours optimized for efficiency without compromising accuracy Absorbance is measured at 450 nm using a standard microplate reader facilitating straightforward integration into laboratory workflows Suitable for research applications requiring specific and reproducible quantification of soluble CD86 this kit provides standardized components and protocols to ensure consistent performance across experimental replicates
Sino Biological Human TIM-1/HAVCR1 Matched ELISA Antibody Pair Set 5 Plates
The Human TIM-1/KIM-1/HACVR ELISA Pair Set is for the quantitative determination of Human TIM-1/KIM-1/HACVR.The Sino Biological ELISA Pair Set is a solid phase sandwich ELISA (Enzyme-Linked Immunosorbent Assay). It utilizes a monoclonal antibody specific for Human TIM-1/KIM-1/HACVR coated on a 96-well plate. Standards and samples are added to the wells, and any Human TIM-1/KIM-1/HACVR present binds to the immobilized antibody. The wells are washed and a horseradish peroxidase conjugated mouse anti-Human TIM-1/KIM-1/HACVR monoclonal antibody is then added, producing an antibody-antigen-antibody "sandwich". The wells are again washed and TMB substrate solution is loaded, which produces color in proportion to the amount of Human TIM-1/KIM-1/HACVR present in the sample. To end the enzyme reaction, the stop solution is added and absorbances of the microwell are read at 450 nm.